Krebs Cycle

1  Krebs Cycle

Outline - Chapter 11 in Text

2  Pyruvate to Oxaloacetate


pyruvate.png
oxaloacetate.png

3  Pyruvate to Acetyl-CoA

See text, Figure 11.4, page 295



4  Pyruvate Dehydrogenase

See text, Table 11.1, page 293



Pyruvate Dehydrogenase Complex contains three 'enzyme activities', with multiple copies of each.

Compact arrangement allows complex reaction sequence to occur very rapidly

5  Krebs Cycle reactions

See Krebs Cycle

or

Krebs Cycle Reactions



Net Reaction:


Acetyl-CoA2 CO2 + CoA
GDP + Pi GTP + H2O
3 NAD + + FAD3 NADH + 3 H + + FADH2


6  Regulation of Krebs Cycle

See text, Figure 11.10, page 302



7  Citrate Metabolism

See text, Figure 11.11, page 303



Citratemit. Citratecyt.

Citratecyt. Oxaloacetate + Acetyl-CoA

Oxaloacetate + NADH Malate + NAD +

Malate + NADP + pyruvate + NADPH + CO2





File translated from TEX by TTH, version 3.02.
On 8 Apr 2002, 13:44.