Mao-Publications

"G-quadruplex and i-motif are mutually exclusive in double-stranded ILPR DNA", Soma Dhakal, Zhongbo Yu, Ryan Konik, Yunxi Cui, Deepak Koirala, and Hanbin Mao. Biophysical Journal, 2012, Accepted.
"The Tertiary DNA Structure in the Single-Stranded hTERT Promoter Fragment Unfolds and Refolds by Parallel Pathways via Cooperative or Sequential Events", Zhongbo Yu; Vanessa Gaerig; Yunxi Cui; HyunJin Kang; Vijay Gokhale; Yuan Zhao; Laurence Hurley; Hanbin Mao. Journal of the American Chemical Society, 2012, 134, 5157-5164 pdf .. Story for this paper

“Intramolecular folding in three tandem guanine repeats of human telomeric DNA", Deepak Koirala, Tomoko Mashimo, Yuta Sannohe, Zhongbo Yu, Hanbin Mao* and Hiroshi Sugiyama*, Chemical Communications, 2012, 48, 2006-2008. pdf.

“A Single-Molecule Platform for Investigation of Interactions between G-quadruplexes and Small-Molecule Ligands”. Deepak Koirala, Soma Dhakal, Beth Ashbridge, Yuta Sannohe, Raphine Rodriguez, Hiroshi Sugiyama, Shankar Balasubramanian, Hanbin Mao*, Nature Chemistry, 2011, 3, 782-787. Story for this paper see pdf.

# See News and Views by Professor Mark Williams, Nature Chemistry, 2011, 3, 754.

“Detection of Single Nucleotide Polymorphism Using Tension-Dependent Stochastic Behavior of a Single-Molecule Template”. Deepak Koirala, Zhongbo Yu, Soma Dhakal, Hanbin Mao*, Journal of the American Chemical Society, 2011, 133, 9988-91. Story for this paper. See pdf.

“Coexistence of an ILPR i-motif and a partially folded structure with comparable mechanical stability revealed at the single molecular level”, Soma Dhakal, Joseph Schonhoft, Deepak Koirala, Zhongbo Yu, Soumitra Basu, Hanbin Mao*, Journal of the American Chemical Society, 2010, 132, 8991-8997. Story for this paper. See pdf.

"Direct Experimental Evidence for Quadruplex-Quadruplex Interaction within the Human ILPR", Joseph Schonhoft, Rabindra Bajracharya, Soma Dhakal, Zhongbo Yu, Hanbin Mao*, Soumitra Basu*, Nucleic Acids Research, 2009, 37, 3310-3320. pdf.

"ILPR G-quadruplexes Formed in Seconds Demonstrate High Mechanical Stabilities", Zhongbo Yu, Joseph D Schonhoft, Soma Dhakal, Rabindra Bajracharya, Ravi Hegde, Soumitra Basu*, and Hanbin Mao*, Journal of the American Chemical Society, 2009, 131,1876–1882. Story for this paper. pdf.

# See comments by Professor Stephen Neidle: Faculty of 1000 Biology J Am Chem Soc.evaluations for Yu Z et al 2009 Feb 11 131 (5):1876-82.

“Thermal Probing of E. coli RNA Polymerase Off-Pathway Mechanisms”, Yara X Mejia, Hanbin Mao, Nancy R Forde, Carlos Bustamante, Journal of Molecular Biology, 2008. 382, 628-637. pdf.

“An Integrated Laser Tweezers Instrument for Microanalysis of Individual Protein Aggregates”, Hanbin Mao and Paul Luchette, Sensors and Actuators B, 2008, 129,764-771. pdf.

“Microanalysis of Clouding Process at the Single Droplet Level”, Paul Luchette, Nebiyu Abiy and Hanbin Mao, Sensors and Actuators B, 2007, 128, 154-160. pdf. Related Patent.

"Temperature Control Methods in a Laser Tweezers System”, Hanbin Mao, J. Ricardo Arias-González, Steve Smith, Ignacio Tinoco Jr. & Carlos Bustamante, Biophysical Journal, 2005, 89:1308-1316. pdf.

“High-Throughput Studies of the Effects of Polymer Structure and Solution Components on the Phase Separation of Thermoresponsive Polymers”, Hanbin Mao, Chunmei Li, Yanjie Zhang, Steven Furyk, Paul S Cremer, David E Bergbreiter, Macromolecules, 2004, 37, 1031-1036.
“Probing the Mechanism of Aqueous Two-Phase System Formation for a-Elastin On-Chip", Yanjie Zhang, Hanbin Mao, Paul S Cremer, Journal of the American Chemical Society, 2003, 125, 15630-15635.
“Measuring LCSTs by Novel Temperature Gradient Methods: Evidence for Intermolecular Interactions in Mixed Polymer Solutions”, Hanbin Mao, Chunmei Li, Yanjie Zhang, David Bergbreiter, Paul S Cremer, Journal of the American Chemical Society, 2003, 125, 2850-2851.
“Investigation of Bivalent Antibody Binding on Fluid Supported Phospholipid Membranes: The Effect of Hapten Density”, Tinglu Yang, Olga K. Baryshnikova, Hanbin Mao, Matthew A. Holden, Paul S Cremer, Journal of the American Chemical Society, 2003, 125, 4779-4784.
“A Versatile, Sensitive Microfluidic Assay for Bacterial Chemotaxis”, Hanbin Mao, Paul Cremer and Michael Manson, Proceedings of National Academy of Sciences of USA, 2003, 100, 5449-5454.
“Reusable Platforms for High-Throughput On-Chip Temperature Gradient Assays”, Hanbin Mao, Matthew A. Holden, Min You, and Paul S. Cremer, Analytical Chemistry, 2002, 74, 5071-5075.
“A Microfluidic Device with a Linear Temperature Gradient for Parallel and Combinatorial Measurements”, Hanbin Mao, Tinglu Yang, Paul Cremer, Journal of the American Chemical Society, 2002, 124, 4432-4435.
“Design and Characterization of Immobilized Enzymes in Microfluidic Systems”, Hanbin Mao, Tinglu Yang, Paul Cremer, Analytical Chemistry, 2002, 74, 379-385.
“Fabrication of Phospholipid Bilayer Coated Microchannels for On-Chip Multivalent Immunoassays”, Tinglu Yang, Seung-Yong Jung, Hanbin Mao and Paul S. Cremer, Analytical Chemistry, 2001, 73, 165-169.



	Group Members -- Research: Microfluidics -- Research: Laser Tweezers

		Selected Publications

"G-quadruplex and i-motif are mutually exclusive in double-stranded ILPR DNA", Soma Dhakal, Zhongbo Yu, Ryan Konik, Yunxi Cui, Deepak Koirala, and Hanbin Mao. Biophysical Journal, 2012, Accepted. "The Tertiary DNA Structure in the Single-Stranded hTERT Promoter Fragment Unfolds and Refolds by Parallel Pathways via Cooperative or Sequential Events", Zhongbo Yu; Vanessa Gaerig; Yunxi Cui; HyunJin Kang; Vijay Gokhale; Yuan Zhao; Laurence Hurley; Hanbin Mao. *Journal of the American Chemical Society,* 2012, 134, 5157-5164 pdf .. Story for this paper “Intramolecular folding in three tandem guanine repeats of human telomeric DNA", Deepak Koirala, Tomoko Mashimo, Yuta Sannohe, Zhongbo Yu, Hanbin Mao* and Hiroshi Sugiyama, Chemical Communications, 2012, 48, 2006-2008. pdf. “A Single-Molecule Platform for Investigation of Interactions between G-quadruplexes and Small-Molecule Ligands”. Deepak Koirala, Soma Dhakal, Beth Ashbridge, Yuta Sannohe, Raphine Rodriguez, Hiroshi Sugiyama, Shankar Balasubramanian, Hanbin Mao, *Nature Chemistry,* 2011, 3, 782-787. Story for this paper see pdf. # See News and Views by Professor Mark Williams, Nature Chemistry, 2011, 3, 754. “Detection of Single Nucleotide Polymorphism Using Tension-Dependent Stochastic Behavior of a Single-Molecule Template”. Deepak Koirala, Zhongbo Yu, Soma Dhakal, Hanbin Mao, Journal of the American Chemical Society,* 2011, 133, 9988-91. Story for this paper. See pdf. “Coexistence of an ILPR i-motif and a partially folded structure with comparable mechanical stability revealed at the single molecular level”, Soma Dhakal, Joseph Schonhoft, Deepak Koirala, Zhongbo Yu, Soumitra Basu, Hanbin Mao, Journal of the American Chemical Society,* 2010, 132, 8991-8997. Story for this paper. See pdf. "Direct Experimental Evidence for Quadruplex-Quadruplex Interaction within the Human ILPR", Joseph Schonhoft, Rabindra Bajracharya, Soma Dhakal, Zhongbo Yu, Hanbin Mao, Soumitra Basu, Nucleic Acids Research, 2009, 37, 3310-3320. pdf. "ILPR G-quadruplexes Formed in Seconds Demonstrate High Mechanical Stabilities", Zhongbo Yu, Joseph D Schonhoft, Soma Dhakal, Rabindra Bajracharya, Ravi Hegde, Soumitra Basu, and Hanbin Mao, Journal of the American Chemical Society, 2009, 131,1876–1882. Story for this paper. pdf. # See comments by Professor Stephen Neidle: Faculty of 1000 Biology J Am Chem Soc.evaluations for Yu Z et al 2009 Feb 11 131 (5):1876-82. “Thermal Probing of E. coli RNA Polymerase Off-Pathway Mechanisms”, Yara X Mejia, Hanbin Mao, Nancy R Forde, Carlos Bustamante, *Journal of Molecular Biology, 2008. 382, 628-637. pdf. “An Integrated Laser Tweezers Instrument for Microanalysis of Individual Protein Aggregates”, Hanbin Mao and Paul Luchette, Sensors and Actuators B,* 2008, 129,764-771. pdf. “Microanalysis of Clouding Process at the Single Droplet Level”, Paul Luchette, Nebiyu Abiy and Hanbin Mao, *Sensors and Actuators B,* 2007, 128, 154-160. pdf. Related Patent. "Temperature Control Methods in a Laser Tweezers System”, Hanbin Mao, J. Ricardo Arias-González, Steve Smith, Ignacio Tinoco Jr. & Carlos Bustamante, *Biophysical Journal, 2005,* 89:1308-1316. pdf. “High-Throughput Studies of the Effects of Polymer Structure and Solution Components on the Phase Separation of Thermoresponsive Polymers”, Hanbin Mao, Chunmei Li, Yanjie Zhang, Steven Furyk, Paul S Cremer, David E Bergbreiter, *Macromolecules, 2004, 37, 1031-1036. “Probing the Mechanism of Aqueous Two-Phase System Formation for a-Elastin On-Chip", Yanjie Zhang, Hanbin Mao, Paul S Cremer, Journal of the American Chemical Society,* 2003, 125, 15630-15635. “Measuring LCSTs by Novel Temperature Gradient Methods: Evidence for Intermolecular Interactions in Mixed Polymer Solutions”, Hanbin Mao, Chunmei Li, Yanjie Zhang, David Bergbreiter, Paul S Cremer, *Journal of the American Chemical Society,* 2003, 125, 2850-2851. “Investigation of Bivalent Antibody Binding on Fluid Supported Phospholipid Membranes: The Effect of Hapten Density”, Tinglu Yang, Olga K. Baryshnikova, Hanbin Mao, Matthew A. Holden, Paul S Cremer, *Journal of the American Chemical Society,* 2003, 125, 4779-4784. “A Versatile, Sensitive Microfluidic Assay for Bacterial Chemotaxis”, Hanbin Mao, Paul Cremer and Michael Manson, *Proceedings of National* *Academy* *of Sciences of* *USA, 2003, 100, 5449-5454. “Reusable Platforms for High-Throughput On-Chip Temperature Gradient Assays”, Hanbin Mao, Matthew A. Holden, Min You, and Paul S. Cremer, Analytical Chemistry, 2002, 74, 5071-5075. “A Microfluidic Device with a Linear Temperature Gradient for Parallel and Combinatorial Measurements”, Hanbin Mao, Tinglu Yang, Paul Cremer, Journal of the American Chemical Society, 2002, 124, 4432-4435. “Design and Characterization of Immobilized Enzymes in Microfluidic Systems”, Hanbin Mao, Tinglu Yang, Paul Cremer, Analytical Chemistry, 2002, 74, 379-385. “Fabrication of Phospholipid Bilayer Coated Microchannels for On-Chip Multivalent Immunoassays”, Tinglu Yang, Seung-Yong Jung, Hanbin Mao and Paul S. Cremer, Analytical Chemistry*, 2001, 73, 165-169.

Selected Publications